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Sunday, May 30, 2010

DIPSAR M PHARM ADMISSIONS 2010


Friday, May 28, 2010

NIPER JEE SYLLABUS

NIPER EXAM PATTERN & SYLLABUS

Entrance pattern:
Well entrance consists of 200 questions in 2 hours. (Please check it in Brochure). Well questions will be very easy so no need to go in depth of the topic. Basic concepts based questions are asked. M. Pharma branches and M.B.A. has a common entrance paper. So read some general knowledge aspects also…………….
This syllabus is just like GATE entrance but more specific in Basic Chemistry instead of medicinal chemistry.
Specialization subjects: What to study…..

Medicinal chemistry and Bulk Drugs (Pharmaceutical Technology)
IUPAC nomenclature, R and S nomenclature, E and Z isomerism, atropiisomerism, Conformations
Hybridization, aromaticity, Huckel’s rule reaction mechanisms- Electrophilic, Nucleophilic, SN1, SN2, SNi, Elimination E1 E2 etc.
Ester hydrolysis, Aac1 Aac2……all eight mechanisms (Jerry march) Markovnikoves rule, Bredts rule, Stereoselectivity, stereospecificity, regioselectivity, chemoselectivity, chirality, stereochemistry, conformations, rearrangements, acids and bases.
Imine-enamine Tautomerism, keto-enol tautomerism, pericyclic reactions, racemic mixture, resolution methods.
Amino acids proteins, various methods for amino acid detection, Ninhydrin test, peptide sequencing, structures of amino acids, essential and nonessential amino acids,
Introduction to thermal methods of analysis like, TGA, DSC, DTA etc.
Carbohydrates classification, osazone test, mutarotation, etc,
Various Heterocycles, Heterocycle synthesis, reactions.
Introduction to Redox reactions.
Spectroscopy: (basics specially): Very very IMP topic. NMR, and C-NMR ranges from Morrison & Boyd or Pavia Mass -Basic concepts about various peaks M+1, molecular ion, base peak etc. (Silverstein) IR - Frequencies of various groups specially carbonyls. UV
Chromatography: Details of every chromatographic method.
Reaction kinetics, first second third and pseudo first order reactions, radio labeling for determination of mechanism.
Common condensation reactions like Aldol, Claisen Perkin, Dickmann, Darzen etc.
Other reactions like Cannizarro’s reaction, Prins reaction, especially reactions of carbonyl compounds.
References:
1. Jerry March
2. Morrison and Boyd (ESPECIALLY Peptide and Carbohydrate chemistry)
3. I. L. Finar Vol-I and Vol-II (Heterocyclic chemistry and organic synthesis)
4. Eliel

Natural Products:
In natural products more stress should be given on phytochemistry part rather than biological aspects.
Methods of extraction, isolation and characterization of natural products. Various separation techniques used for isolation of natural products.
Biosynthetic pathways.
Primary metabolites, their examples.
Secondary metabolites, various classes of secondary metabolites (e.g. Alkaloids, glycosides, tannins, lignans, saponins, lipids, flavonoids, coumarins, anthocyanidines etc.). Here most imp. Part is chemistry of these classes.
Important therapeutic classes: antidiabetics, hepatoprotectives, immmunomodulators, neutraceuticals, natural products for gynecological disorders, anti-cancer, anti-viral (mainly anti-HIV), adaptogens etc.
Dietary antioxidants, Marine natural products, Plant growth regulators.
Spectroscopy: Basic concepts of UV, NMR, IR and Mass spectroscopy. Give more stress on IR and NMR.
Stereochemistry: Basic concepts.
Fischer, sawhorse and newmon projection formulaes.
Biological sources of important classes of natural products. (Selected ones only)
Standardization of natural products.
What is difference between natural products and pharmacognosy?
References:
1. For various therapeutic classes: Trease and Evans
2. For spectroscopy: Silverstein, Pavia, Kemp.
3. For stereochemistry: I.L. Finar vol-II

Pharmacology and toxicology:
Pharmacokinetics, pharmacodynamics, pharmacological effect, desired, undesired, toxic, adverse effects.
Bioavailability, bioequivalence, various factors of ADME. (From Bramhankar)
Drug metabolism: various pathways and other details.
Drug interactions, agonist, antagonist, partial agonist, protein binding, drug distribution, distribution volume, excretion pathways etc.
Pharmacological screening: general principles, various screening models, screening methodologies (in vitro and in vivo tests).
Mechanism of drug action, drug-receptor interaction.
Various adrenergic, cholinergic and other receptors
Detailed study of CNS pharmacology
Study of basis of threshold areas of work in NIPER in pharmacology dept. mentioned in brochure.
Diseases: study of the pharmacology of the diseases and drugs used with mode of action especially of diabetes, malaria, leishmaniasis, TB, hypertension, myocardial ischemia, inflammation, and immunomodualtion.
Chemotherapy and pathophysiology- knowledge of antibiotics, their mode of action and the microorganisms responsible for various common diseases.
Bioassay methods, various requirements. Brief knowledge of the statistical tests.
References:
1. Rang and Dale (ALL CHEMOTHERAPY CLASSES OF DRUGS. IF YOU READ THE WHOLE BOOK, then nothing else is needed)
2. F. S. K. Barar
3. Wilson and Griswold (for Mechanism)
4. Kasture (for Bioassay and Screening)

Pharmaceutics and formulation (Pharmaceuticl Technology)
Drug delivery systems (DDS):
NDDS models, osmotic pumps, various release patterns eg. Controlled release, delayed release. Sustained release etc., order of release. Oral controlled DDS, factors affecting controlled release.
Carriers in DDS: polymers and their classification, types, carbohydrates, surfactants, proteins, lipids, prodrugs etc.
Transdermal drug delivery systems (TDDS): principles, absorption enhancers, evaluation of TDDS.
Parenterals: requirements, advantages, disadvantages, release pattern, route of drug delivery.
Drug targeting: microspheres, nano particles, liposomes, monoclonal antibodies, etc.
Preformulation detailed.
Complexation, solubilization, polymerization, viscosity measurements.
Dosage form development- stages, implications of dosage form.
Additives of formulation, types, examples, advantages, disadvantages, drug excipient interaction, incompatibility, various types of incompatibilities.
Dosage forms: solid (tablets, capsules, pills etc), liquid (emulsion, suspension etc), sterile (injectables), aerosols. Principles, advantages, disadvantages and problems.
Coating - in detail.
Packaging: materials, labeling etc. Types of containers (e.g. Tamper-proof containers)
In process controls, Product specification, documentation.
Compartmental modeling. (From Bramhankar)
Bioavailability, bioequivalence studies. Methods of improvement of oral bioavailability.
Evaluation of formulation, principles and methods of release control in oral formulations.
References:
1. Lachmann (ALL new and old techniques in Pharmaceutical Industry)
2. Alfred Martin (ALL physical chemistry BASICS)
3. Remington’s Pharmaceutical Sciences
4. Notes of Gudsurkar Sir (Most important)
5. Banker series.
6. other: Bramhankar, , Liberman Series

Pharmaceutical analysis:
Stability testing of pharmaceuticals, various stability tests, kinetic studies, shelf life determination, thermal stability, formulation stability.
Various analytical techniques
Tests: physical and chemical tests, limit tests, microbiological tests, biological tests, disintegration and dissolution tests.
Spectroscopic methods; UV, NMR, IR, MS, FT-IR, FT-NMR, ATR (Attenuated Total Reflectance), FT-Raman- basics and applications.
Thermal techniques: DSC, DTA, TGA, etc.
Particle sizing: law of diffraction.
Electrophoresis: capillary electrophoresis.
Chromatography- detailed.
QA and QC: GLP, TQM, ISO system.
Preformulation, cyclodextrin inclusion compounds
Solubility: pH, pka, surfactant HLB values, Rheology.
Crystallinity, polymorphism, solvates and hydrates, crystal habits, porosity, surface area flow properties.
Dosage forms, Stages of dosage form development
Osmolality, osmolarity, osmotic pressure, conductivity, Preservatives, Media for bioassay.
References:

1. Willard
2. Silverstein (Mass Spectroscopy)
3. William Kemp (NMR)
4. Pavia (for spectroscopy)
5. Others like Alfred Martin, Chatwal (UV), Garry Christen (Chemical Methods)

Biotechnology:Pharmaceutical technology biotechnology
Genetic Engg: Gene expression, mutation, replication, transcription, translation, recombination, bacteriophages.
Cloning: methods, isolation of nucleic acids, enzymes in cloning (restriction endonucleases, DNA ligase, DNA gyrase, polymerases etc...), functions of these enzymes, Pallindromes.
Fermentation: fermenters, fermentation process, its regulation, conditions, bioprocessors, various enzymes in fermentation technology. Fermentation of Antibiotics, vitamins, amino acids, hydroxy acids such as lactic acid etc. Chemical engg. aspects realated to fermentation
Gene therapy: methods and applications.
Monoclonal antibodies, insulin, interferons, enkephalins, angiotensin analogues and other peptides.
References:
1. Vyas and Dixit
2. IP Appendices

Practice of Pharmacy:
The best part for the preparation for this best reference for this would be Remington’s Pharmaceutical Sciences. This branch is quite new here, so till dates students of branch used to do case study of prescriptions in Fortis hospital, PGI Chandigarh and govt. college chd... This is much like pharmacology and drug-drug interactions and different interactions are emphasized. Diabetes, heart diseases are main area of study……….

Pharmacoinformatics:
Terminologies related with new emerging informatics e.g. proteomics, genomics, QSAR (2D, 3D, regression, correlation).
References:
Foye, Williams and Lemke, Medicinal chemistry, 5th/6th edition, chapter 1-6. (Computational drug design and molecular modeling).

Others:
Statistics, general mathematics and aptitude questions. Use MBA entrance test books like CET or CAT in MBA. Additionally some general awareness questions.
NIPER’s thrust areas are:
Microbial and viral diseases: Yeast, and fungi.
Parasitic and tropical diseases: Malaria, Leishmaniasis, amoebiasis, etc.
Metabolic Disorders: Diabetes
Strokes
Peptide and carbohydrate chemistry.
Genomics and proteomics: yeast and fungi
Hormonal disorders: TRH related diseases.

Thursday, May 27, 2010

BIT MESRA RANCHI M PHARM ADMISSIONS

BIT Mesra

Applications are invited from eligible candidates for admission to the following postgraduate programmes of the Institute for the session 2010-11:


M. Pharm in Pharmaceutics, Pharmaceutical Chemistry, Pharmacognosy, Pharmacology, Clinical Research, and Quality Assurance & Regulatory Affairs,

M.S. 
Clinical Research & Pharmacovigilance, and 

PG Diploma in Bioanalytical Techniques, and Pharmacovigilance

Please click here to download the Application Form

 Last date for receipt of completed forms for all programmes at Mesra is 22 June 2010



Saturday, May 22, 2010

SHOBHIT UNIVERSITY M PHARM ADMISSIONS 2010

Master of Pharmacy (M.Pharm.)

(M.Pharm. - Two Years Full Time)
Specializations :
  • Pharmaceutics
  • Pharmacology
  • Pharmaceutical Chemistry
Eligibility:
B.Pharm. degree with a minimum of 55% marks from a recognized University, preferably with valid GATE score.
Program Fee:
Tuition Fee :  Rs.1,50,000/- per annum
University Charges:  Rs. 20,000/- per annum

Admission Procedure

  • Admission in the M.Pharm. program shall be based on an online entrance test, followed by an interview by a group of experts. Due weightage will be given to B.Pharm. percentage, experience etc.

  • The Test will be based on B.Pharm. syllabus (GATE pattern), comprising of 50 multiple choice questions to be attempted in 90 minutes.

  • The  Entrance Test shall be conducted by Shobhit University at its campus.

  • Girl candidates / Wards of Defence Persons/ Candidates from J&K and North East states shall be given an additional weightage of 5%.
  • Seats/Branches in the above programs are allotted on the basis of preferences indicated at the time of counseling, in order of merit. Candidates must go through instructions. Ignorance of laid down instruction shall be responsibility of the candidate.
  • Decisions of the Admission Committee in all regards shall be binding and final.

    Admission Application Form (in Word .doc)
    Admission Application Form (in Adobe pdf)


    All applications on the prescribed Application Form shall be sent along with a demand draft of non-refundable processing charge of  Rs.1100/- only, in favour of  Shobhit University payable at Meerut to;

    Admission Cell
    SHOBHIT UNIVERSITY
    NH-58, Modipuram
    Meerut – 250 110,
    Uttar Pradesh, India  

    Last Date to Apply : 12 June, 2010

    Date of Entrance Test : 20 June, 2010

Wednesday, May 19, 2010

Amrita School of Pharmacy M PHARM ADMISSION

M PHARM-
PHARMACY PRACTICE
PHARMACEUTICS
PHARMACEUTICAL CHEMISTRY

ADMISSION PROCEDURE
Selection is based on the rank obtained in the All India entrance test conducted by Amrita Vishwa Vidyapeetham

DATE OF EXAMINATION   June 6, 2010

COST OF APPLICATION   1250

Exam Centres 

Amrita School of Medicine,
Amrita Institute of Medical Sciences, 
AIMS-Ponekkara, Kochi. KERALA - 682 041.

Prospectus and Application forms will be available from the branches of Dhanalakshmi Bank and Federal Bank from 26th April 2010 onwards.
DD to be drawn in the name of AMRITA VISHWA VIDYAPEETHAM. Payable at KOCHI. 
Requests for applications may be sent to:
                                                 THE ADMISSION CO ORDINATOR
                                                 Office of Admissions,
                                                 Amrita Health Sciences Campus,
                                                 Amrita Institute of Medical Sciences & Research Centre,
                                                 AIMS Ponekkara Post,
                                                 Kochi, Kerala 682 041.
                                                 Phone:0484-285 8036 / 8037 / 5651
                                                 Email: ugadmissions@aims.amrita.edu
                                                 Fax: 0484-280 2020 / 2051

IMPORTANT DATES
Date of commencement of sale of application forms  : 26 April 2010 

Last date of sale of application forms                          :31 May 2010 

Last date of receipt of duly completed application forms:01 June 2010 

Date of Examination                                       : SUNDAY, 6 June 2010 
LINK

ANDHRA UNIVERSITY M PHARM EVENING PROGRAMME

Applications are invited from eligible candidates for admission into the
following courses for academic year 2010-2011 offered in A.U College of
Engineering (A) through AUCET-2010


THROUGH ENTRANCE TEST: 5 Year Integrated Dual Degree B.E.+M.E./
B.Tech.+M.Tech. Courses in Computer Science & Software Engineering,
Computer Science & Information Technology, Civil Engineering, Mechanical
Engineering, Electrical & Electronics Engineering and Electronics &
Communication Engineering ; 2 Year Double Degree MS/M.Tech. Courses
in Software Engineering, Digital signal Processing and Tele Communication
Systems and B.Engg. in Aircraft Engineering (Twinning Program).


WITHOUT ENTRANCE TEST: M.E./M.Tech / M.Pharm / MBA Evening
Courses for locally employed personnel.


Application form and Information Brochure can be had from the Office of
the Principal, A.U College of Engineering, Visakhapatnam on payment of
Rs. 500/-. Applications can also be had by post from the Director by sending
a DD for Rs. 550/- (Rs. 50/- for postage) drawn in favour of The Director,
Directorate of Admissions, payable at Visakhapatnam before 25-05-2010


IMPORTANT DATES

1. Commencement of Sale of applications : 17-05-2010
2. Last date for receipt of filled in applications without fine : 02-06-2010
3. Last date for receipt of filled in applications with a fine of Rs. 500/- : 19-06-2010
4. Date of Entrance Test (Tentative). : 21-06-2010



M.E. / M.Tech. / M. Pharm. Evening Courses (for locally employed personnel)
(i) The M.E./M.Tech./M.Pharm. Evening courses are meant for eligible locally employed
personnel.
(ii) Requirement for admission is a minimum aggregate of 50% marks for M.E./M.Tech. and
M.Pham. Courses in the qualifying examination.
(iii) Admission into these courses shall be processed as per the following order of preference (i)
Qualified GATE / GPAT Score, (ii) Rank in PGECET-2010 and (iii) percentage of marks
obtained in B.E./B.Tech./B.Pharm.
(iv) Separate application has to be submitted for courses in each department if the candidate is
desirous of applying for courses in more than one department based on the eligibility criteria.



Wednesday, May 12, 2010

Punjab Drug Inspector Posts (37) Recruitment

GOVERNMENT OF PUNJAB
DEPARTMENT OF HEALTH AND FAMILY WELFARE PUNJAB
(HEALTH-1 BRANCH) CHANDIGARH
PUBLIC NOTICE – RECRUITMENT
Drug Inspector:37 Posts
Applications are invited for recruitment on regular basis to 37 posts of Drug Inspectors which are lying vacant in the institutions of Health Department Punjab. Number of posts may increase or decrease.
The detail of posts in various categories and their pay scale is as per Annexure-A and B. No Person shall be appointed to the services by direct recruitment, unless he passes the following educational qualifications and experience:-
Educational and other Qualifications for Drug Inspector:
Should possess a degree in Pharmacy or Pharmaceutical Sciences or Medicine with specialization in Clinical Pharmacology or Microbiology from a recognized University or institution:
Provided that only those inspectors:-
i) Who have not less than 18 months experience in the manufacture of at least one of the substances specified in Schedule “C” of the Drugs and cosmetic Rules 1945; or
ii) Who have not less than 18 months experience in the testing of at least one of the substances in Schedule “c” of the Drugs and cosmetic Rules 1945; in a laboratory approved for this purpose by the licensing authority; or
iii) Who have gained experience of not less than 3 years in the inspection of farms manufacturing any of the substances in Schedule “c” of the Drugs and Cosmetic Rules 1945 during the tenure of their services as Drugs inspectors; Shall be authorized to inspect the manufacture of the substances mentioned in Schedule “c” of the Drugs and cosmetic Rules 1945.
iv) Knowledge of Punjabi Language up to Matriculation Standard. Candidates who do not possess the qualification shall have to acquire this qualification within six months of their joining the service failing which their services shall be terminated.
5. AGE LIMIT:-
18 to 35 years on 1-1-2010.
NOTE:
i) The upper age limit for Punjab State, other States or Central Government Employees is relaxable up 45 years.
ii) The upper age limit prescribed above is relaxable up to a maximum of five years for Scheduled Castes and Scheduled Tribes of all States and Backward Classes of Punjab.
iii) The upper age limit for widows and certain other categories of women of Punjab is relaxable up to 40 years.
iv) An ex-serviceman of Punjab domicile shall be allowed to deduct the period of his service in the Armed Forces of the Union from his actual age and if the resultant age does not exceed the maximum age limit prescribed for direct appointment to such a vacancy in the service Rules concerned by more than three years, he shall be deemed to satisfy the condition regarding age limit.
6. Other Terms and Conditions:
1. Candidates will be considered in the category in which they are applying on merit i.e. General Category & Reserve Category.
2. Reservation Policy will be applicable as per instructions of the State Government.
Candidates who have applied against Scheduled Caste Category but if he/she comes in merit at par with General Category will be selected against the General Category seats.
3. Application should be submitted by post/ by hand as per the format along with the attested copies of testimonials/ Degrees etc. Addressed to Director Health and Family Welfare Punjab Room No. 219, 1st Floor, Parivar Kalyan Bhawan, Sector 34-A, Chandigarh Pin Code 160022. (Tel. 0172-5074351, Mobile 98720-74403).
4. The candidates are requested to send attested copies of their testimonials. Attested copies of certificates having Date of Birth, Having Punjabi Passed up to Matriculation or above, a copy of Punjab Domicile certificate, a copy of cast certificate in case of S.C./B.C candidates. B.C. candidates must attach the required certificate of current year.
7. The application forms complete in all respects, must reach before 5 p.m. on or before dated 24-5-2010. The applications received later than the prescribed date shall be summarily rejected. Wrongly filled or incomplete applications shall also be summarily
rejected and the candidature cancelled.
6. Incomplete applications and incomplete educational qualification will not be considered/entertained.
Advertisement for Punjab Drug Inspector Posts (37) Recruitment
Application Form
Categoriwise breakup of Posts

Saturday, May 8, 2010

Guru Ghasidas University M.Pharm. Admissions 2010-2011 Academic Session


Admission to M.Pharm. shall be on the basis of GATE/GPAT score.

Last Date for receipt of completed application forms: 31/05/2010

Fore more details visit the following links
Admission Notification
Admission Brochure VET-2010
Application form VET 2010


GPAT 2010 SOLUTIONS/KEY

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Sunday, May 2, 2010

GPAT 2010 ANSWER KEY

CLICK HERE TO DOWNLOAD GPAT 2010 ANSWER KEY


Download here